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The Hospital of The University of Pennsylvania

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Clinical PBMCancer Supportive CareLymphedema TreatmentAcademic ResearchMedical SupervisionComplex Conditions

Guest Reviews

(210 reviews)

87% of patients recommend HUP according to Healthgrades. The hospital earns high marks for subspecialty expertise, cancer care, and research-driven treatment protocols. Photobiomodulation is deployed as part of clinical programs at Penn's cancer centers and rehabilitation medicine division.

Contact & Hours

Phone: (215) 590-1000
Website: Visit website
Hours:
note: Open 24 hours, 7 days a week (main hospital); specialty clinic hours vary

About The Hospital of The University of Pennsylvania

The Hospital of the University of Pennsylvania (HUP) stands as one of the nation's premier academic medical centers, anchoring Penn Medicine's clinical enterprise at its main campus on Spruce Street in West Philadelphia. Ranked consistently among America's top hospitals by U.S. News & World Report, HUP combines world-class subspecialty care with a research enterprise that places it at the frontier of therapeutic innovation — including photobiomodulation therapy. Penn's engagement with photobiomodulation is both clinical and investigational. The Perelman Center for Advanced Medicine, housed within HUP's campus, has been the site of clinical research examining PBM therapy's efficacy in head and neck cancer-related lymphedema — one of the most debilitating and undertreated sequelae of cancer therapy. A pilot feasibility study conducted at the Penn Abramson Cancer Center's Head and Neck Cancer Clinics validated PBM as a safe and promising intervention for this patient population, establishing a clinical pathway for broader deployment within Penn's oncology supportive care infrastructure. Beyond oncology, Penn's Department of Radiation Oncology at the Perelman Center and the broader Penn Medicine rehabilitation network provide additional contexts in which photobiomodulation is deployed for wound healing acceleration, oral mucositis prevention in bone marrow transplant patients, and musculoskeletal pain management. The Zhu Lab at Perelman School of Medicine conducts active photomedicine research that continues to expand the evidence base for PBM at the molecular and clinical levels. For patients navigating cancer treatment, complex rehabilitation, or chronic inflammatory conditions in the greater Philadelphia area, the Hospital of the University of Pennsylvania offers access to photobiomodulation embedded within one of the most comprehensively supported and research-active clinical environments in the United States.

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